Understanding how different brain regions reactivate memories related to rewards

Role of multi-regional neuronal reactivations in reward-based memories

NIH-funded research Johns Hopkins University · NIH-10875435

This study looks at how our brains remember things that make us feel good, both when we're awake and asleep, to help us understand how we form and strengthen these memories, especially when we're trying to achieve our goals.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10875435 on NIH RePORTER

What this research studies

This research investigates how the brain reactivates memories associated with rewards across various regions. It focuses on the processes that occur during both wakefulness and sleep, where neurons involved in these memories are reactivated. By examining these multi-regional neuronal activities, the study aims to uncover how memories are formed and consolidated, particularly in relation to goal-directed tasks. The research employs advanced techniques to monitor neuronal activity across different brain circuits simultaneously.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing memory issues related to Alzheimer's disease or other forms of dementia.

Not a fit: Patients with memory issues not related to reward-based learning or those with other neurological disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new insights into memory formation and potential therapeutic strategies for memory-related disorders.

How similar studies have performed: Previous research has shown promising results in understanding memory processes through similar multi-regional approaches, indicating potential for success in this area.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.