Understanding how different brain regions reactivate memories related to rewards
Official title: Role of multi-regional neuronal reactivations in reward-based memories
Funded at Johns Hopkins University · NIH-10875435 · Data updated 2026-11-12
This study looks at how our brains remember things that make us feel good, both when we're awake and asleep, to help us understand how we form and strengthen these memories, especially when we're trying to achieve our goals.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $121,608 |
| NIH project number | 5K99DA059024-02 |
| Project ID | NIH-10875435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing memory issues related to Alzheimer's disease or other forms of dementia.
✕Less likely to help
Patients with memory issues not related to reward-based learning or those with other neurological disorders may not benefit from this research.
What this research studies
This research investigates how the brain reactivates memories associated with rewards across various regions. It focuses on the processes that occur during both wakefulness and sleep, where neurons involved in these memories are reactivated. By examining these multi-regional neuronal activities, the study aims to uncover how memories are formed and consolidated, particularly in relation to goal-directed tasks. The research employs advanced techniques to monitor neuronal activity across different brain circuits simultaneously.
Why it matters
Potential benefit: If successful, this research could lead to new insights into memory formation and potential therapeutic strategies for memory-related disorders.
How similar studies have gone: Previous research has shown promising results in understanding memory processes through similar multi-regional approaches, indicating potential for success in this area.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Drieu, Celine — Johns Hopkins University
- Study coordinator: Drieu, Celine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.