Understanding how different antibodies work against the AIDS virus
Physical Resources Core
This study is looking at how different types of antibodies and their helpers in the immune system can help fight the AIDS virus, and it hopes to find ways to make vaccines and treatments better for people living with or at risk of AIDS.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10894645 on NIH RePORTER |
What this research studies
This research focuses on the role of Fc receptors (FcRs) and antibodies in fighting the AIDS virus. It aims to explore how variations in antibody types and FcRs affect the immune response, particularly in both humans and rhesus macaques. By analyzing genetic diversity and its impact on antibody functionality, the research seeks to improve the effectiveness of immunization strategies. Patients may benefit from insights that could lead to better treatments and preventive measures against AIDS.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for or living with HIV/AIDS who are interested in new treatment options.
Not a fit: Patients who are not affected by HIV/AIDS or who are not at risk for the virus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective vaccines and treatments for AIDS.
How similar studies have performed: Previous research has shown promise in understanding antibody responses in similar contexts, suggesting potential for success in this area.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Pollara, Justin Joseph — Duke University
- Study coordinator: Pollara, Justin Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.