Understanding how different animal brains control behavior and interact with their environment

Quantifying organism-environment interactions in a new model system for neuroscience

NIH-funded research Harvard University · NIH-11036699

This study looks at how the acoel worm, a small marine creature, interacts with its surroundings and how its special brain affects its behavior, helping us learn more about how different brains work and how they influence actions in various animals.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHarvard University NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-11036699 on NIH RePORTER

What this research studies

This research investigates how the acoel worm, Hofstenia miamia, interacts with its environment and how its unique brain structure influences behavior. By studying this marine invertebrate, researchers aim to uncover general principles of brain function and behavior that differ from traditional model organisms like flies and mice. The project will utilize quantitative methods to analyze the worm's complex behaviors and the resulting changes in its aquatic habitat, providing insights into brain regeneration and distributed computation. This approach could lead to a better understanding of behavioral mechanisms across diverse species.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in the biological mechanisms of behavior and brain function.

Not a fit: Patients with conditions unrelated to neurological function or behavior may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of brain function and behavior, potentially informing treatments for neurological conditions.

How similar studies have performed: While studies on model organisms have been successful, this research approach using Hofstenia miamia is novel and has not been extensively tested.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.