Understanding how diet influences gut bacteria and their metabolism
Official title: Dissecting the effect of diet on gut microbiome metabolism
Funded at Princeton University · NIH-10997937 · Data updated 2026-11-12
This study is looking at how what you eat, like protein and fiber, can change the bacteria in your gut and the helpful substances they produce, which could help people with gut health issues like inflammatory bowel disease and obesity.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | December 16, 2024 |
| Project end | December 15, 2028 |
| Funding year | 2024 |
| Award (this year) | $32,974 |
| NIH project number | 1F30DK139739-01A1 |
| Project ID | NIH-10997937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions influenced by gut microbiome metabolism, such as inflammatory bowel disease or obesity.
✕Less likely to help
Patients with no gastrointestinal issues or those not interested in dietary modifications may not benefit from this research.
What this research studies
This research investigates how different dietary components, such as protein and fiber, affect the metabolism of gut bacteria and the production of important metabolites like indole and phenol. By using advanced techniques like liquid chromatography-mass spectrometry and 16S rRNA sequencing, the study aims to explore how dietary modifications can change the composition of gut microbiota and their metabolic outputs. The findings could provide insights into how diet can be used to manage conditions related to gut health, such as inflammatory bowel disease and obesity.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that improve gut health and manage microbiome-related diseases.
How similar studies have gone: Previous research has shown that dietary changes can significantly impact gut microbiome composition and function, suggesting a promising avenue for further exploration.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Abusalim, Jenna — Princeton University
- Study coordinator: Abusalim, Jenna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.