Understanding how diet and metabolism affect liver disease in Hispanic/Latino adults
Official title: Epidemiology of diet, metabolism and non-alcoholic fatty liver disease in Hispanic/Latino adults
Funded at Albert Einstein College of Medicine · NIH-10930071 · Data updated 2026-11-12
This study is looking at how what you eat and your metabolism affect liver health, especially for Hispanic and Latino adults who are more likely to have non-alcoholic fatty liver disease, and it aims to find ways to prevent this condition through better diet and lifestyle choices.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | September 15, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $645,272 |
| NIH project number | 5R01DK134672-02 |
| Project ID | NIH-10930071 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Hispanic and Latino adults who may be at risk for non-alcoholic fatty liver disease due to factors like obesity, diabetes, or poor dietary habits.
✕Less likely to help
Patients who do not identify as Hispanic or Latino or those without risk factors for non-alcoholic fatty liver disease may not benefit from this research.
What this research studies
This research investigates the relationship between diet, metabolism, and non-alcoholic fatty liver disease (NAFLD) specifically in Hispanic and Latino adults, who are at a higher risk for this condition. The study will analyze a large sample of participants to explore how factors like obesity, diabetes, and dietary habits contribute to the development of NAFLD and its complications. By utilizing advanced imaging techniques, researchers aim to identify early signs of liver disease and develop low-cost screening tests based on dietary and metabolic markers. The ultimate goal is to create effective interventions to prevent NAFLD through dietary changes and other therapeutic approaches.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and screening methods for non-alcoholic fatty liver disease in Hispanic and Latino populations.
How similar studies have gone: Previous research has shown that dietary and metabolic factors significantly influence liver disease, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Kaplan, Robert C — Albert Einstein College of Medicine
- Study coordinator: Kaplan, Robert C
Related research
Other NIH-funded projects on the same topics.
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Role of fat droplets in liver fat and inflammatory signals in NAFLD
A study at Johns Hopkins will explore how fat droplets in the liver influence molecules that drive inflammation and progression of non-alcoholic fatty liver disease (NAFLD) in adults.
-
Them1 Inhibitors to Help Treat Fatty Liver Disease
Aims to develop and test small molecule drugs that block Them1 to help people with non-alcoholic fatty liver disease (NAFLD).
-
How the TET1 gene affects non-alcoholic fatty liver disease
Researchers are looking at whether changes in the TET1 gene and DNA 'tagging' (methylation) play a role in adult non-alcoholic fatty liver disease.
-
Hepatocellular Genetic Clues for Fatty Liver in Hispanic Adults
A large NIH grant helps researchers study why fatty liver develops in Hispanic adults and how genetics interact with lifestyle to affect risk.
-
Toxic fats, vitamin B12 loss, and AHR may drive fatty liver disease
This grant looks at how certain environmental chemicals may trigger liver damage linked to fatty liver disease and how a vitamin found in the blood could be affected.
-
Glutamine and T cells in fatty liver disease
A study explores how liver glutamine levels affect inflammatory CD4+ T cells in fatty liver disease to find potential new ways to reduce liver inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.