Understanding how diet affects immune and metabolic health
Genetic Modeling of Diet, NFkB, and Metabolic Interactions
This study looks at how what we eat affects our immune system and metabolism, using fruit flies to help us understand how poor diets can lead to problems like obesity and diabetes, with the hope of finding new diet tips or treatments that could help people with these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University Health Science Ctr NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-11085211 on NIH RePORTER |
What this research studies
This research investigates the interactions between diet, immune responses, and metabolism using model organisms like fruit flies. By studying how over-nutrition and dietary imbalances activate immune signaling pathways, the research aims to uncover the underlying mechanisms that lead to metabolic disorders such as obesity and diabetes. The approach combines genetic modeling and cell-based studies to explore how these systems are regulated and how they can be influenced by dietary factors. Patients may benefit from insights that could lead to new dietary recommendations or treatments for metabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals at risk for obesity or metabolic disorders due to dietary habits.
Not a fit: Patients who are not affected by metabolic disorders or do not have dietary concerns may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating metabolic disorders linked to diet.
How similar studies have performed: Previous research has shown success in using model organisms to study metabolic and immune interactions, suggesting that this approach is promising.
Where this research is happening
College Station, United States
- Texas A&m University Health Science Ctr — College Station, United States (Active)
Researchers
- Principal investigator: Karpac, Jason S — Texas A&m University Health Science Ctr
- Study coordinator: Karpac, Jason S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.