Understanding how diabetes contributes to heart disease
Cellular and molecular mechanisms of diabetic atherosclerosis
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10895528
This study is looking at how a new treatment that helps the liver could improve heart health for people with diabetes by preventing heart disease, and it aims to find out if this approach can help reduce the risk of serious problems like heart attacks.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10895528 on ClinicalTrials.gov |
What this research studies
This research investigates the cellular and molecular processes that lead to heart disease in individuals with diabetes. It focuses on a new treatment that targets liver function to improve insulin sensitivity and reduce fat buildup in the liver. By using animal models, the study aims to understand how this treatment can prevent the development of atherosclerosis, a condition that narrows blood vessels and increases the risk of heart attacks. Patients may benefit from insights into new therapies that could improve heart health in those with diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type 2 diabetes who are at risk for cardiovascular disease.
Not a fit: Patients without diabetes or those with other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce the risk of heart disease in diabetic patients.
How similar studies have performed: Previous research has shown promising results with similar approaches targeting metabolic processes to reduce cardiovascular risks in diabetic patients.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOEDEKE, LEIGH — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: GOEDEKE, LEIGH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus