Understanding how diabetes affects the right side of the heart
Official title: Mechanisms of right ventricular dysfunction in type 2 diabetes
Funded at University of Wyoming · NIH-11192965 · Data updated 2026-11-12
This study is looking at how type 2 diabetes can affect the right side of the heart, which is often ignored, and it aims to understand the role of fatty acids and stress in causing this damage, so we can find better ways to help people with diabetes keep their hearts healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wyoming NIH-funded |
| Lab location | 1 site (Laramie, United States) |
| Project start | September 25, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $323,277 |
| NIH project number | 1R56HL164328-01A1 |
| Project ID | NIH-11192965 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with type 2 diabetes who may be experiencing heart-related issues.
✕Less likely to help
Patients without diabetes or those with heart conditions unrelated to diabetes may not benefit from this research.
What this research studies
This research investigates how type 2 diabetes leads to dysfunction in the right ventricle of the heart, which is often overlooked compared to the left ventricle. The study aims to identify specific mechanisms that cause damage to the right ventricle, focusing on how fatty acids and oxidative stress contribute to this condition. By examining these processes, the research seeks to improve our understanding of heart health in diabetic patients and potentially lead to new treatment strategies. Patients may be involved in assessments that help clarify these mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for heart dysfunction in patients with diabetes.
How similar studies have gone: While there has been significant research on left ventricular dysfunction in diabetes, this focus on right ventricular mechanisms is relatively novel and untested.
Where this research is happening
-
University of Wyoming
Laramie, United States Active
Researchers
- Principal investigator: Bruns, Danielle Reuland — University of Wyoming
- Study coordinator: Bruns, Danielle Reuland
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.