Understanding how diabetes affects eye health and vision loss

Characterizing ocular structures and local retinal function in the progression of different objective phenotypes of prediabetes and type 2 diabetes

NIH-funded research University of Houston · NIH-11066500

This study is looking at how prediabetes and type 2 diabetes can affect your eye health, especially in causing vision problems, and it aims to find early signs of eye damage so that we can help prevent vision loss for people at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11066500 on NIH RePORTER

What this research studies

This research investigates the impact of prediabetes and type 2 diabetes on eye health, specifically focusing on how these conditions lead to diabetic retinopathy, a major cause of vision loss. By utilizing advanced imaging techniques and objective health assessments, the study aims to identify early signs of eye damage in patients with glucose dysregulation. The goal is to develop methods for early diagnosis and intervention that could help prevent vision loss in at-risk individuals. Participants will undergo various tests to evaluate their ocular structures and functions in relation to their diabetes status.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with prediabetes or type 2 diabetes.

Not a fit: Patients who do not have prediabetes or type 2 diabetes, or those with advanced diabetic retinopathy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and prevention strategies for vision loss in individuals with diabetes.

How similar studies have performed: Previous research has shown promising results in using advanced imaging techniques to detect early signs of diabetic retinopathy, indicating that this approach may be effective.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.