Understanding how depression affects young people with autism
Neural Mechanisms of Depressive Symptoms in Youth with Autism SpectrumDisorder
This study is looking at how the brains of teenagers with autism and depression work differently, so we can find better ways to help them feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emma Pendleton Bradley Hospital NIH-funded |
| Lab location | 1 site (Riverside, UNITED STATES) |
| Project ID | NIH-10893042 on NIH RePORTER |
What this research studies
This research investigates the neural mechanisms that contribute to depressive symptoms in adolescents with autism spectrum disorder (ASD). By using advanced imaging techniques, the study aims to identify specific brain connectivity patterns and white matter changes associated with depression in this population. The research involves scanning both children with ASD and age-matched controls to compare their brain structures and functions. Ultimately, the goal is to develop targeted treatments that can improve mental health outcomes for these young individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 16 who have been diagnosed with autism spectrum disorder and exhibit depressive symptoms.
Not a fit: Patients outside the age range of 12 to 16 or those without a diagnosis of autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for depression in youth with autism.
How similar studies have performed: Previous research has shown promising results in understanding the neural correlates of depression in various populations, suggesting potential for success in this novel approach.
Where this research is happening
Riverside, UNITED STATES
- Emma Pendleton Bradley Hospital — Riverside, United States (Active)
Researchers
- Principal investigator: Radoeva, Petya D — Emma Pendleton Bradley Hospital
- Study coordinator: Radoeva, Petya D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.