Understanding how depression affects older adults through anxiety and inflammation
Experimental model of depression in aging: anxiety, inflammation, and reward mechanisms
['FUNDING_CAREER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11045627
This study is looking at how depression, anxiety, and inflammation affect older adults' feelings of joy and motivation, with the goal of finding better ways to detect and treat depression in this age group.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11045627 on ClinicalTrials.gov |
What this research studies
This research investigates the complex relationship between depression, anxiety, and inflammation in older adults. It aims to understand how these factors contribute to a loss of pleasure and motivation, which are common in late-life depression. By examining biological markers and behavioral responses, the study seeks to identify mechanisms that could lead to better detection and treatment of depression in this population. Participants may undergo assessments and interventions that explore the impact of inflammation on mood and motivation.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing symptoms of depression and anxiety.
Not a fit: Patients who are not experiencing depression or anxiety may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for depression in older adults, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the link between inflammation and mood disorders, indicating that this approach may yield valuable insights.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOYLE, CHLOE — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: BOYLE, CHLOE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.