Understanding how depression affects memory in older adults
Phenotype Predictors of Cognitive Outcomes in Geriatric Depression
['FUNDING_R01'] · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · NIH-11079573
This research helps us understand how stress impacts mood and memory changes in older adults with depression.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT (nih funded) |
| Locations | 1 site (FARMINGTON, UNITED STATES) |
| Trial ID | NIH-11079573 on ClinicalTrials.gov |
What this research studies
This project builds on previous findings to explore how stress affects mood and thinking abilities over time in older adults experiencing depression. Researchers are looking at how severe or ongoing stress might lead to changes in behavior, mood, sleep, appetite, and social engagement. They are also examining how these stress effects might show up in the brain's structure and function. The goal is to better understand why some older adults with depression experience cognitive decline and how stress plays a role.
Who could benefit from this research
Good fit: This research is for older adults with late-life depression, as well as older adults who have never experienced depression, who are at least 21 years old.
Not a fit: Patients who are not older adults or do not have a history of depression may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better ways to predict and prevent memory problems in older adults with depression by understanding the role of stress.
How similar studies have performed: This is a renewal grant extending previous findings, indicating that prior work has laid a foundation for this continued investigation into stress and late-life depression outcomes.
Where this research is happening
FARMINGTON, UNITED STATES
- UNIVERSITY OF CONNECTICUT SCH OF MED/DNT — FARMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STEFFENS, DAVID C. — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
- Study coordinator: STEFFENS, DAVID C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease