Understanding how delta-catenin affects social behavior
Official title: The roles of delta-catenin in social behavior
Funded at Colorado State University · NIH-10987007 · Data updated 2026-11-12
This study is looking at how a gene called delta-catenin affects social behavior, especially for people with autism, to understand how changes in this gene might lead to challenges in social interactions and find new ways to help improve those interactions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | November 15, 2023 |
| Project end | October 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $305,813 |
| NIH project number | 5R01MH132921-02 |
| Project ID | NIH-10987007 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with autism spectrum disorder, particularly those with a family history of delta-catenin mutations.
✕Less likely to help
Patients without autism spectrum disorder or those who do not have a genetic predisposition related to delta-catenin may not benefit from this research.
What this research studies
This research investigates the role of delta-catenin in regulating social behavior, particularly in relation to autism spectrum disorders. It explores how mutations in the delta-catenin gene can disrupt synaptic activity, leading to social impairments. By studying the effects of delta-catenin deficiency in animal models, the research aims to uncover the underlying mechanisms that connect synaptic function to social behavior. The findings could provide insights into potential therapeutic targets for improving social interactions in individuals with autism.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance social functioning in individuals with autism.
How similar studies have gone: Previous studies have shown promising results in understanding the genetic and synaptic underpinnings of autism, suggesting that this research builds on established findings.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Kim, Seonil — Colorado State University
- Study coordinator: Kim, Seonil
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.