Understanding how delirium relates to biological age in older adults with brain injuries
Official title: Characterizing the Relationship Between Delirium and Biological Age in Traumatic Brain Injury: Implications for Cognitive Decline in Older Adults
Funded at University of California, San Francisco · NIH-10973533 · Data updated 2026-11-12
This study is looking at how delirium relates to biological age in older adults who have had mild brain injuries, with the goal of finding ways to better understand and treat delirium to help improve health outcomes for these patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $243,000 |
| NIH project number | 1K76AG083285-01A1 |
| Project ID | NIH-10973533 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults who have experienced mild traumatic brain injuries and are at risk for delirium.
✕Less likely to help
Patients who are younger than 21 years old or do not have a history of traumatic brain injury may not benefit from this research.
What this research studies
This research investigates the connection between delirium and biological age in older adults who have experienced mild traumatic brain injuries. The project aims to identify risk factors for delirium and track the long-term clinical outcomes associated with it. By focusing on older hospitalized patients, the research seeks to improve diagnostics and treatment strategies for delirium, which is a significant risk factor for cognitive decline and Alzheimer's disease. The principal investigator, Dr. Sara LaHue, will undergo advanced training in aging biology and geriatric research methods to enhance her expertise in this area.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for delirium, ultimately enhancing cognitive health and quality of life for older adults.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between delirium and cognitive decline, suggesting that this approach has potential for significant advancements.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Lahue, Sara Catherine — University of California, San Francisco
- Study coordinator: Lahue, Sara Catherine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.