Understanding how deep brain stimulation affects language production in Parkinson's patients
Defining the role of the subthalamic nucleus in language production through deep brain stimulation
This study is looking at how a treatment called deep brain stimulation affects the way people with Parkinson's disease speak, focusing on how it helps them find and use words more easily.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10595041 on NIH RePORTER |
What this research studies
This research investigates the impact of deep brain stimulation (DBS) of the subthalamic nucleus on language production in patients with Parkinson's disease. It aims to identify how this therapy influences verbal fluency and the underlying mechanisms involved in word production. By studying patients with unilateral DBS implants, the research will explore the role of the basal ganglia in language processing and how cognitive changes may occur post-treatment. The findings could help refine therapeutic approaches and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Parkinson's disease who are considering or have undergone deep brain stimulation therapy.
Not a fit: Patients who do not have Parkinson's disease or who are not candidates for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing language deficits in Parkinson's patients undergoing deep brain stimulation.
How similar studies have performed: Previous research has shown that deep brain stimulation can affect cognitive functions, but this specific investigation into language production is relatively novel.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Rodriguez-Porcel, Federico — Medical University of South Carolina
- Study coordinator: Rodriguez-Porcel, Federico
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.