Understanding how COVID-19 viruses evolve and affect the immune system

CEIRR: COVID-19 Research Activities

NIH-funded research Johns Hopkins University · NIH-11144905

This study looks at how COVID-19 viruses change and spread, focusing on both people and animals, to help us understand how our immune system fights off COVID-19 and other similar viruses, which could lead to better vaccines in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11144905 on NIH RePORTER

What this research studies

This research investigates the factors that influence the evolution and transmission of COVID-19 viruses, particularly SARS-CoV-2. It involves cohort studies and sampling from both humans and animals to gather data on infection and immune responses. By analyzing these factors, the research aims to improve our understanding of how the immune system protects against COVID-19 and other respiratory viruses, which could inform future vaccination strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have been infected with COVID-19 or are at risk of infection, as well as those involved in vaccination studies.

Not a fit: Patients who are not affected by respiratory viruses or have no risk factors for COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccines and treatments for COVID-19 and related respiratory viruses.

How similar studies have performed: Other research has shown success in understanding viral evolution and immune responses, making this approach promising.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.