Understanding how COVID-19 affects the gastrointestinal system
Mechanisms of Gastrointestinal COVID-19
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10866413
This study is looking at how COVID-19 affects stomach issues like nausea and belly pain, especially in people with inflammatory bowel disease, to better understand why these symptoms happen and how the virus interacts with our gut.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10866413 on ClinicalTrials.gov |
What this research studies
This research investigates the gastrointestinal symptoms experienced by COVID-19 patients, such as nausea and abdominal pain. It aims to understand how the SARS-CoV-2 virus interacts with intestinal cells and the immune response in both healthy individuals and those with inflammatory bowel disease (IBD). By using advanced techniques like gene sequencing and organoid models, the study will explore the cellular mechanisms and factors that influence the severity of gastrointestinal symptoms in COVID-19 patients.
Who could benefit from this research
Good fit: Ideal candidates include individuals who have experienced gastrointestinal symptoms during COVID-19, particularly those with inflammatory bowel disease.
Not a fit: Patients who have not experienced gastrointestinal symptoms related to COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for gastrointestinal symptoms in COVID-19 patients.
How similar studies have performed: Other research has shown that understanding viral interactions with the gut can lead to significant insights into disease mechanisms, suggesting potential for success in this area.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CIORBA, MATTHEW AARON — WASHINGTON UNIVERSITY
- Study coordinator: CIORBA, MATTHEW AARON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.