Understanding how COVID-19 affects the brain differently in men and women
Sex specific immune response to SARS-CoV-2 leads to chronic neurologic symptoms
This study is looking at the long-lasting brain and nerve problems some people have after getting over COVID-19, especially how these issues might be different for men and women, to help find better ways to support those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10913521 on NIH RePORTER |
What this research studies
This research investigates the long-term neurological symptoms that some individuals experience after recovering from COVID-19, focusing on how these symptoms may differ between men and women. The study aims to understand the immune response triggered by the virus, particularly the inflammatory reactions that can lead to brain issues such as encephalitis and neuropsychiatric symptoms. By analyzing blood samples and neurological assessments, researchers hope to uncover the underlying mechanisms that contribute to these chronic symptoms. This could help identify patients at risk and develop targeted interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have recovered from COVID-19 and are experiencing ongoing neurological or neuropsychiatric symptoms.
Not a fit: Patients who have not been infected with COVID-19 or those without any neurological symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from long-term neurological effects of COVID-19.
How similar studies have performed: Other research has indicated that understanding immune responses in viral infections can lead to significant insights into long-term health effects, suggesting this approach has potential for success.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Mccullough, Louise D. — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Mccullough, Louise D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.