NIH-funded research R01 grant

Understanding how COVID-19 affects people with alcohol use disorder

Official title: Characterize multifaceted interactions between COVID-19 and alcohol use disorder based on real-time analysis of electronic health records of 62 million adult patients

Funded at Case Western Reserve University · NIH-10687823 · Data updated 2026-11-12

This study is looking at how COVID-19 and alcohol use disorder (AUD) affect each other, especially for adults who might be more at risk, and it hopes to find ways to help those who are struggling with both during the pandemic.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University
NIH-funded
Lab location1 site (Cleveland, United States)
Project startSeptember 22, 2021
Project endAugust 31, 2025
Funding year2023
Award (this year)$362,250
NIH project number5R01AA029831-03
Project IDNIH-10687823 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults with a history of alcohol use disorder, particularly those who have been affected by COVID-19.

Less likely to help

Patients without a history of alcohol use disorder or those who have not been impacted by COVID-19 may not benefit from this research.

What this research studies

This research investigates the complex interactions between COVID-19 and alcohol use disorder (AUD) by analyzing electronic health records from 62 million adult patients. It aims to understand how individuals with AUD may be more susceptible to COVID-19 and how COVID-19 may increase the risk of developing AUD. The study will also explore the prevalence of other psychiatric disorders and substance use issues among patients affected by both conditions. By identifying these relationships, the research seeks to inform timely interventions that could help protect vulnerable patients during the pandemic and beyond.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing the health of individuals with alcohol use disorder during and after the COVID-19 pandemic.

How similar studies have gone: Other research has shown that understanding the interplay between mental health and infectious diseases can lead to significant advancements in patient care, suggesting this approach has potential for success.

Where this research is happening

  • Case Western Reserve University
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Xu, Rong — Case Western Reserve University
  • Study coordinator: Xu, Rong

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.