Understanding how coronary blood flow is regulated
Disentangling the Mechanisms of Coronary Blood Flow Regulation through Multi-scale Modeling
This study is looking at how blood flows to the heart and what affects it, especially when the heart might not be getting enough oxygen, to help find better treatments for heart problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11059152 on NIH RePORTER |
What this research studies
This research investigates the complex mechanisms that control blood flow to the heart muscle, ensuring it receives enough oxygen to function properly. By using advanced modeling techniques, the study aims to uncover how various factors influence coronary blood flow, especially during conditions that can lead to reduced blood supply. The goal is to enhance our understanding of how the heart adapts to different physiological challenges, which could lead to improved treatments for heart-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular conditions that affect blood flow to the heart.
Not a fit: Patients without any cardiovascular issues or those who are not experiencing any symptoms related to heart function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment strategies for patients with heart disease.
How similar studies have performed: Previous research has shown success in understanding coronary blood flow regulation, but this approach aims to provide deeper insights into the mechanisms involved.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Figueroa, Carlos Alberto — University of Michigan at Ann Arbor
- Study coordinator: Figueroa, Carlos Alberto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.