Understanding how copper affects energy production in cells
Official title: Mitochondrial Copper Biology
Funded at Texas A&m Agrilife Research · NIH-11003282 · Data updated 2026-11-12
This study is looking at how copper helps our cells grow and produce energy, especially in the tiny powerhouses called mitochondria, and it aims to find out how we can use copper to prevent serious health issues like Menkes disease, which happens when the body doesn't get enough copper.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m Agrilife Research NIH-funded |
| Lab location | 1 site (College Station, UNITED STATES) |
| Project start | February 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $536,690 |
| NIH project number | 5R35GM152102-02 |
| Project ID | NIH-11003282 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants and children diagnosed with congenital copper deficiency disorders.
✕Less likely to help
Patients with conditions unrelated to copper metabolism or those who do not have a deficiency in copper may not benefit from this research.
What this research studies
This research investigates the role of copper as a vital nutrient for the growth and energy production in cells, particularly focusing on its function in mitochondrial metabolism. The study aims to uncover the mechanisms of copper transport and its importance in preventing fatal disorders linked to copper deficiency, such as Menkes disease. By using various biological models, the researchers will explore how copper is delivered to mitochondria and how it can restore normal cellular respiration. The findings could lead to the development of new treatments for conditions caused by copper deficiency.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for life-threatening disorders caused by copper deficiency.
How similar studies have gone: Previous research has shown promise in using similar approaches to address copper-related disorders, indicating potential for success in this area.
Where this research is happening
-
Texas A&m Agrilife Research
College Station, United States Active
Researchers
- Principal investigator: Gohil, Vishal Mahendrasingh — Texas A&m Agrilife Research
- Study coordinator: Gohil, Vishal Mahendrasingh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.