Understanding how COPD progresses in patients

Structural Determinants of Disease Progression in COPD

['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10809749

This study is looking at how the lungs change in people with COPD to find better ways to treat the condition and help doctors predict how it might progress for each person.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded)
Locations1 site (BIRMINGHAM, UNITED STATES)
Trial IDNIH-10809749 on ClinicalTrials.gov

What this research studies

This research investigates the structural changes in the lungs that contribute to the progression of chronic obstructive pulmonary disease (COPD). It aims to identify specific pathways involved in airway and alveolar remodeling, which are crucial for developing targeted therapies. By analyzing the disease's progression in individuals, the study seeks to establish reliable biomarkers that can predict how COPD will affect each patient. This approach may lead to more personalized treatment strategies for those suffering from COPD.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with chronic obstructive pulmonary disease.

Not a fit: Patients with mild respiratory issues or those without a COPD diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and more effective treatments for COPD, ultimately enhancing patient outcomes.

How similar studies have performed: Previous research has shown promise in understanding COPD progression, but this study aims to explore novel pathways that have not been extensively tested.

Where this research is happening

BIRMINGHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.