NIH-funded research NIH-funded research

Understanding how cognitive-behavioral therapy helps treat food avoidance in children and adolescents

Official title: Cognitive and neural mechanisms of cognitive-behavioral therapy for avoidant/restrictive food intake disorder

Funded at Massachusetts General Hospital · NIH-10924032 · Data updated 2026-11-12

This study is looking at a new type of therapy for kids and teens aged 10-18 who struggle with avoiding certain foods due to fear or anxiety, to see if it helps them feel more comfortable eating a wider variety of foods.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 7, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$1,055,907
NIH project number5R61MH129331-02
Project IDNIH-10924032 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children and adolescents aged 10-18 who are diagnosed with avoidant/restrictive food intake disorder.

Less likely to help

Patients who do not have ARFID or are outside the age range of 10-18 years may not benefit from this research.

What this research studies

This research investigates the effectiveness of a specialized cognitive-behavioral therapy (CBT-AR) designed for children and adolescents with avoidant/restrictive food intake disorder (ARFID). The study will involve 50 youth participants aged 10-18, who will be randomly assigned to receive either CBT-AR or nutrition counseling over 15 weekly sessions conducted via telehealth. The goal is to understand how this therapy can reduce food avoidance by targeting both psychological and neural mechanisms related to fear and food neophobia. By using a randomized controlled trial approach, the research aims to provide insights into the treatment of ARFID, which currently lacks evidence-based options.

Why it matters

Potential benefit: If successful, this research could lead to an effective treatment for ARFID, improving nutritional intake and overall quality of life for affected youth.

How similar studies have gone: Previous research has shown promising results with cognitive-behavioral therapy for various eating disorders, suggesting potential success for this novel approach to ARFID.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Lawson, Elizabeth Austen — Massachusetts General Hospital
  • Study coordinator: Lawson, Elizabeth Austen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.