Understanding how cognitive aging differs in adults with and without dementia
Official title: Defining rates of cognitive aging in adults with and without dementia using the CODA cohort
Funded at Brown University · NIH-10947431 · Data updated 2026-11-12
This study is looking at how our thinking skills change as we get older, especially comparing healthy adults to those with Alzheimer's or similar conditions, to help improve care for people with dementia.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $319,000 |
| NIH project number | 1R03AG088764-01 |
| Project ID | NIH-10947431 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults aged 21 and older, both with and without a diagnosis of Alzheimer's disease or related dementias.
✕Less likely to help
Patients who are younger than 21 or do not have any cognitive aging concerns may not benefit from this research.
What this research studies
This research aims to measure the normal rate of cognitive aging in adults who do not have neurocognitive disorders and compare it to the accelerated cognitive aging seen in individuals with Alzheimer's disease or related dementias. By analyzing data from the Children of the Depression cohort, the study will estimate cognitive performance and identify how quickly cognitive abilities decline with age. The research will also link this data with Medicare records to track dementia diagnoses over time, providing a clearer picture of cognitive aging patterns. This information could help in developing better care strategies for those affected by dementia.
Why it matters
Potential benefit: If successful, this research could provide valuable insights into cognitive aging, potentially leading to improved diagnosis and treatment strategies for dementia.
How similar studies have gone: Previous research has successfully identified cognitive aging patterns, but this study aims to establish a normative reference that is currently lacking.
Where this research is happening
-
Brown University
Providence, United States Active
Researchers
- Principal investigator: Kunicki, Zachary — Brown University
- Study coordinator: Kunicki, Zachary
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.