Understanding how cilia function and their role in cell communication
The Biology of Motile Cilia
This study is looking at tiny hair-like structures on cells called cilia, using a green alga to learn how they move and work, with the hope of finding out how problems with cilia can cause health issues for people with certain conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-11075135 on NIH RePORTER |
What this research studies
This research investigates the biology of motile cilia, which are tiny hair-like structures on cells that help them sense their environment and communicate with each other. The study uses a green alga called Chlamydomonas as a model organism to explore how cilia move and how they are assembled. By examining the molecular mechanisms behind ciliary function, the research aims to uncover new insights into how defects in cilia can lead to various health issues known as ciliopathies. The approach combines biochemical analysis with genetic techniques to provide a comprehensive understanding of ciliary biology.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with ciliopathies or related conditions that affect ciliary function.
Not a fit: Patients with conditions unrelated to ciliary function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases caused by ciliary defects.
How similar studies have performed: Previous research has shown promising results in understanding ciliary function, indicating that this approach has potential for significant discoveries.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: King, Stephen M — University of Connecticut Sch of Med/dnt
- Study coordinator: King, Stephen M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.