Understanding how cilia affect the development of brain cells called astrocytes
Official title: The Novel Role of Cilia in Astrocyte Sevelopment
Funded at Emory University · NIH-11052628 · Data updated 2026-11-12
This study is looking at how tiny hair-like structures on cells, called cilia, help brain cells called astrocytes grow and work properly, which could give us clues about brain disorders related to these cells and help us find better treatments.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | March 13, 2023 |
| Project end | January 12, 2026 |
| Funding year | 2025 |
| Award (this year) | $44,270 |
| NIH project number | 5F31NS125984-03 |
| Project ID | NIH-11052628 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals with neurodevelopmental disorders or conditions linked to astrocyte dysfunction.
✕Less likely to help
Patients with conditions unrelated to astrocyte function or those without neurodevelopmental disorders may not benefit from this research.
What this research studies
This research investigates the role of cilia, which are tiny hair-like structures on cells, in the development of astrocytes, a type of brain cell crucial for supporting neurons. The study aims to uncover how these cilia influence the growth and function of astrocytes, particularly during critical stages of brain development. By examining the effects of cilia on astrocyte proliferation and morphology, the research seeks to provide insights into the mechanisms behind neurodevelopmental disorders linked to astrocyte dysfunction. This foundational knowledge could lead to better understanding and potential treatments for conditions associated with abnormal astrocyte development.
Why it matters
Potential benefit: If successful, this research could lead to new insights into neurodevelopmental disorders and potential therapeutic strategies for conditions caused by astrocyte dysfunction.
How similar studies have gone: While the role of cilia in neuron development has been studied, the specific investigation of astrocyte cilia is relatively novel and has not been extensively tested.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Bear, Rachel Marie — Emory University
- Study coordinator: Bear, Rachel Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.