Understanding how chronic pain develops in endometriosis from adolescence to adulthood
Official title: Identifying plasma proteomic profiles of chronic pain development in endometriosis from adolescence to adulthood
Funded at Brigham and Women's Hospital · NIH-10685659 · Data updated 2026-11-12
This study is looking at blood samples from young people with endometriosis to find clues that could help predict and manage chronic pain, aiming to improve treatment options and reduce the need for pain medications like opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,689,739 |
| NIH project number | 1DP2HD112176-01 |
| Project ID | NIH-10685659 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents and young adults diagnosed with endometriosis who experience chronic pelvic pain.
✕Less likely to help
Patients who do not have endometriosis or those who are not experiencing chronic pain related to the condition may not benefit from this research.
What this research studies
This research investigates the plasma proteomic profiles associated with the development of chronic pain in individuals with endometriosis, focusing on those from adolescence to adulthood. By analyzing blood samples, the study aims to identify biological markers that could help predict and manage pain more effectively. The goal is to improve pain management strategies, particularly for adolescents and young adults who are at risk of developing chronic pain due to endometriosis. This approach may lead to better treatment options and reduce reliance on opioids.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for individuals suffering from endometriosis, particularly in younger populations.
How similar studies have gone: Other research has shown promise in identifying biological markers for chronic pain in various conditions, suggesting that this approach could yield valuable insights for endometriosis as well.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Sasamoto, Naoko — Brigham and Women's Hospital
- Study coordinator: Sasamoto, Naoko
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.