Understanding how chronic pain develops in endometriosis from adolescence to adulthood

Identifying plasma proteomic profiles of chronic pain development in endometriosis from adolescence to adulthood

NIH-funded research Brigham and Women's Hospital · NIH-10685659

This study is looking at blood samples from young people with endometriosis to find clues that could help predict and manage chronic pain, aiming to improve treatment options and reduce the need for pain medications like opioids.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10685659 on NIH RePORTER

What this research studies

This research investigates the plasma proteomic profiles associated with the development of chronic pain in individuals with endometriosis, focusing on those from adolescence to adulthood. By analyzing blood samples, the study aims to identify biological markers that could help predict and manage pain more effectively. The goal is to improve pain management strategies, particularly for adolescents and young adults who are at risk of developing chronic pain due to endometriosis. This approach may lead to better treatment options and reduce reliance on opioids.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults diagnosed with endometriosis who experience chronic pelvic pain.

Not a fit: Patients who do not have endometriosis or those who are not experiencing chronic pain related to the condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for individuals suffering from endometriosis, particularly in younger populations.

How similar studies have performed: Other research has shown promise in identifying biological markers for chronic pain in various conditions, suggesting that this approach could yield valuable insights for endometriosis as well.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.