Understanding how chronic blood clots affect children's health and exercise
Functional Characterization of Children with Chronic Venous Thromboembolic Disease
This study is looking at how chronic blood clots in children can cause problems like trouble breathing and difficulty exercising, and it aims to find out if these issues come from the heart, lungs, or muscles, while also considering how weight might affect things; the goal is to help create better exercise and weight plans to improve the health and activity levels of kids dealing with this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10886666 on NIH RePORTER |
What this research studies
This research investigates the impact of chronic venous thromboembolic disease in children, focusing on symptoms like shortness of breath and exercise intolerance. Using advanced imaging techniques, the study aims to identify whether these symptoms are due to heart, lung, or muscle issues, and how factors like obesity may play a role. By examining patients at different stages post-diagnosis, the research seeks to uncover the underlying mechanisms affecting their quality of life and physical activity. The findings could lead to tailored exercise programs or weight management strategies to improve health outcomes for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with venous thrombosis or pulmonary embolism.
Not a fit: Patients who do not have a history of venous thrombosis or pulmonary embolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance the quality of life and physical activity levels for children suffering from chronic venous thromboembolic disease.
How similar studies have performed: Previous research has shown that understanding the mechanisms behind exercise intolerance in similar patient populations can lead to significant improvements in treatment approaches.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Zia, Ayesha — Ut Southwestern Medical Center
- Study coordinator: Zia, Ayesha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.