Understanding how chromatin states are regulated in cells
ATP-dependent and independent mechanisms of regulating chromatin states
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11079438
This study is looking at how certain proteins help keep our cells organized and working properly, which is important for things like staying healthy and preventing diseases like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11079438 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that control chromatin states, which are crucial for maintaining cellular identity and differentiation. By examining both ATP-dependent and independent processes, the study aims to uncover how chromatin remodeling proteins function and interact within cells. Utilizing advanced biophysical techniques, the research will explore the differences in mechanisms among various chromatin regulators and their roles in cellular processes. This work could provide insights into how changes in chromatin states may contribute to diseases like cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or conditions related to chromatin dysregulation.
Not a fit: Patients with conditions unrelated to chromatin regulation or those not diagnosed with cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating cancers and other diseases linked to chromatin regulation.
How similar studies have performed: Previous research has shown promising results in understanding chromatin mechanisms, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NARLIKAR, GEETA J — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: NARLIKAR, GEETA J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.