Understanding how cholinergic regulation affects blood vessel health
Official title: Mentoring in cholinergic regulation of vascular oxidation
Funded at Vanderbilt University Medical Center · NIH-11067739 · Data updated 2026-11-12
This study is helping new scientists at Vanderbilt University learn how the nervous system affects blood vessel health, especially in African American communities, to find better ways to prevent heart problems and improve treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | April 20, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $115,983 |
| NIH project number | 5K24HL165163-03 |
| Project ID | NIH-11067739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are African American individuals experiencing cardiovascular health issues.
✕Less likely to help
Patients who do not identify as African American or those without cardiovascular health concerns may not receive direct benefits from this research.
What this research studies
This research focuses on mentoring emerging scientists at Vanderbilt University Medical Center to enhance their skills in studying how cholinergic regulation impacts vascular health, particularly in African American populations. The project aims to improve understanding of endothelial dysfunction, a condition that can lead to cardiovascular disease, by exploring the role of reactive oxygen species and the vagus nerve. Through collaboration with experts in bioelectronic medicine, the research seeks to develop innovative approaches to improve vascular function and reduce cardiovascular risks. Patients may benefit from advancements in treatment strategies that arise from this mentoring initiative.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cardiovascular disease, particularly in African American patients who are disproportionately affected.
How similar studies have gone: Previous research has shown success in addressing endothelial dysfunction and cardiovascular health disparities, indicating that this approach has potential for meaningful advancements.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Shibao, Cyndya Adriana — Vanderbilt University Medical Center
- Study coordinator: Shibao, Cyndya Adriana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.