Understanding how choline affects cell health and disease
Deciphering the role of phospholipid homeostasis in physiology and disease
This study is looking at how choline, an important nutrient, helps keep our cells healthy and how it might affect different diseases, so that patients can learn more about how choline impacts their health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11139569 on NIH RePORTER |
What this research studies
This research investigates the role of choline, a vital nutrient, in maintaining cell health and its implications for various diseases. By studying how choline is transported into cells and its effects on cellular processes like membrane formation and gene regulation, the research aims to uncover new insights into its importance for overall health. The team utilizes advanced techniques, including genome-wide association studies and CryoEM, to identify key transport proteins and their functions. Patients may benefit from a better understanding of how choline metabolism impacts their health and disease outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who may have conditions related to choline metabolism or cellular health.
Not a fit: Patients who are under 21 years old or do not have any metabolic or cellular health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cellular health and treating diseases linked to choline metabolism.
How similar studies have performed: Previous research has shown promising results in understanding the role of choline in cellular processes, indicating that this approach has potential for significant findings.
Where this research is happening
New York, United States
- Rockefeller University — New York, United States (Active)
Researchers
- Principal investigator: Kenny, Timothy Cole — Rockefeller University
- Study coordinator: Kenny, Timothy Cole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.