Understanding how Chlamydia infections affect men who have sex with women
Official title: The natural history of C. trachomatis urethral infections in men who have sex with women
Funded at Indiana University Indianapolis · NIH-10880559 · Data updated 2026-11-12
This study is looking at how Chlamydia infections in men who have sex with women can affect their chances of getting reinfected and what factors, like certain bacteria in their bodies, might play a role, all with the goal of finding ways to help stop the spread of Chlamydia to women.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | July 5, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $792,498 |
| NIH project number | 5R01AI177002-02 |
| Project ID | NIH-10880559 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men who have had sexual contact with women diagnosed with Chlamydia trachomatis.
✕Less likely to help
Patients who are not sexually active or who have never been diagnosed with Chlamydia may not benefit from this research.
What this research studies
This research investigates the natural history of Chlamydia trachomatis infections in men who have sex with women, focusing on how these infections may lead to immunity or reinfection. The study aims to identify factors that contribute to Chlamydia reinfections, such as the presence of specific microbiome compositions and other sexually transmitted infections. By analyzing immune responses and the microbiome in men, the research seeks to uncover insights that could help prevent the spread of Chlamydia to women.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing Chlamydia reinfections in women, ultimately reducing reproductive health complications.
How similar studies have gone: While there has been research on Chlamydia infections, this specific focus on male immunity and microbiome interactions is relatively novel.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Nelson, David Emmet — Indiana University Indianapolis
- Study coordinator: Nelson, David Emmet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.