Understanding how Chlamydia infections affect men who have sex with women

The natural history of C. trachomatis urethral infections in men who have sex with women

NIH-funded research Indiana University Indianapolis · NIH-10880559

This study is looking at how Chlamydia infections in men who have sex with women can affect their chances of getting reinfected and what factors, like certain bacteria in their bodies, might play a role, all with the goal of finding ways to help stop the spread of Chlamydia to women.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-10880559 on NIH RePORTER

What this research studies

This research investigates the natural history of Chlamydia trachomatis infections in men who have sex with women, focusing on how these infections may lead to immunity or reinfection. The study aims to identify factors that contribute to Chlamydia reinfections, such as the presence of specific microbiome compositions and other sexually transmitted infections. By analyzing immune responses and the microbiome in men, the research seeks to uncover insights that could help prevent the spread of Chlamydia to women.

Who could benefit from this research

Good fit: Ideal candidates for this research are men who have had sexual contact with women diagnosed with Chlamydia trachomatis.

Not a fit: Patients who are not sexually active or who have never been diagnosed with Chlamydia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing Chlamydia reinfections in women, ultimately reducing reproductive health complications.

How similar studies have performed: While there has been research on Chlamydia infections, this specific focus on male immunity and microbiome interactions is relatively novel.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.