Understanding how children's throat muscles work during speech using MRI

Evaluating Velopharyngeal Function During Phonation in Children Utilizing Static MRI

NIH-funded research East Carolina University · NIH-10926831

This study is looking at how children with cleft palate or speech issues use their throat muscles when they talk, using special imaging to see how everything works, so doctors can better plan treatments and surgeries for them.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionEast Carolina University NIH-funded
Lab location1 site (Greenville, United States)
Project IDNIH-10926831 on NIH RePORTER

What this research studies

This research investigates the velopharyngeal function in children, particularly those with a history of cleft palate or velopharyngeal insufficiency. By utilizing magnetic resonance imaging (MRI), the study aims to visualize the muscles and structures involved in speech production during specific phonation tasks. The goal is to establish normative data for how these structures behave during speech, which can aid in surgical planning and treatment for affected children. The research also considers racial differences in anatomy, which may influence speech physiology.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years, particularly those with a history of cleft palate or velopharyngeal insufficiency.

Not a fit: Patients who do not have any history of speech or velopharyngeal issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide critical insights that improve surgical outcomes and speech therapy for children with velopharyngeal insufficiency.

How similar studies have performed: Other research has successfully utilized MRI to study similar anatomical and functional aspects in children, making this approach promising.

Where this research is happening

Greenville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.