Understanding how children respond to behavioral therapy for tics

Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-10928268

This study is looking at how kids aged 10-17 with chronic tics respond to a popular therapy called Comprehensive Behavioral Intervention for Tics (CBIT), to find out who benefits the most and how the treatment works, while they attend eight weekly sessions and have some brain scans done to see how their tics improve.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-10928268 on ClinicalTrials.gov

What this research studies

This research investigates how children aged 10-17 respond to Comprehensive Behavioral Intervention for Tics (CBIT), a leading treatment for chronic tics. The study aims to identify factors that predict which children will benefit from CBIT and to understand the key components of the therapy that lead to improvement. Participants will undergo eight weekly therapy sessions, with assessments before, after, and three months later to measure changes in tic severity and brain function. By using advanced imaging techniques like fMRI and EEG, the research seeks to uncover the brain mechanisms involved in tic suppression.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 10-17 who experience chronic tics.

Not a fit: Patients who do not have chronic tics or are outside the age range of 10-17 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for children with chronic tics, improving their quality of life.

How similar studies have performed: Previous research has shown promising results in understanding behavioral interventions for tics, but this study aims to provide novel insights into the underlying mechanisms.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.