Understanding how children respond to behavioral therapy for tics
Official title: Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
Funded at University of Minnesota · NIH-10928268 · Data updated 2026-11-12
This study is looking at how kids aged 10-17 with chronic tics respond to a popular therapy called Comprehensive Behavioral Intervention for Tics (CBIT), to find out who benefits the most and how the treatment works, while they attend eight weekly sessions and have some brain scans done to see how their tics improve.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $771,128 |
| NIH project number | 5R01MH131645-02 |
| Project ID | NIH-10928268 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 10-17 who experience chronic tics.
✕Less likely to help
Patients who do not have chronic tics or are outside the age range of 10-17 years may not benefit from this research.
What this research studies
This research investigates how children aged 10-17 respond to Comprehensive Behavioral Intervention for Tics (CBIT), a leading treatment for chronic tics. The study aims to identify factors that predict which children will benefit from CBIT and to understand the key components of the therapy that lead to improvement. Participants will undergo eight weekly therapy sessions, with assessments before, after, and three months later to measure changes in tic severity and brain function. By using advanced imaging techniques like fMRI and EEG, the research seeks to uncover the brain mechanisms involved in tic suppression.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for children with chronic tics, improving their quality of life.
How similar studies have gone: Previous research has shown promising results in understanding behavioral interventions for tics, but this study aims to provide novel insights into the underlying mechanisms.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Wang, Sonya Grace — University of Minnesota
- Study coordinator: Wang, Sonya Grace
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.