NIH-funded research R03 grant

Understanding how children read using only one side of their brain

Official title: Plasticity of the reading brain: Insights from isolated left and right hemispheres

Funded at Mgh Institute of Health Professions · NIH-10870249 · Data updated 2026-11-12

This study is looking at how kids who have had surgery to remove one side of their brain learn to read using the other side, and it aims to find out what makes their brains work differently compared to kids who don’t have this experience, all to help improve teaching methods for children with reading challenges.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionMgh Institute of Health Professions
NIH-funded
Lab location1 site (Charlestown, UNITED STATES)
Project startApril 1, 2024
Project endMarch 31, 2026
Funding year2024
Award (this year)$160,957
NIH project number1R03HD114969-01
Project IDNIH-10870249 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who have undergone hemispherectomy and are learning to read.

Less likely to help

Children who have not had hemispherectomy or do not have reading disabilities may not benefit from this research.

What this research studies

This research investigates how children who have had surgery to remove one hemisphere of their brain learn to read using the remaining hemisphere. By comparing their reading abilities with those of typically developing peers, the study aims to uncover the unique brain configurations that support reading in these children. The research will utilize advanced imaging techniques to assess the structural and functional aspects of the brain related to reading. This work is particularly important for enhancing educational strategies for children with acquired reading disabilities.

Why it matters

Potential benefit: If successful, this research could lead to improved educational interventions and support for children with reading disabilities resulting from hemispherectomy.

How similar studies have gone: Previous research has shown that children can develop reading skills using a single hemisphere, indicating potential for success in this area of investigation.

Where this research is happening

  • Mgh Institute of Health Professions
    Charlestown, United States
    Active

Researchers

  • Principal investigator: Christodoulou, Joanna — Mgh Institute of Health Professions
  • Study coordinator: Christodoulou, Joanna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.