Understanding how children and adolescents in Uganda get infected with KSHV.
Characterizing determinants of primary KSHV infection among children and adolescents in Uganda
['FUNDING_R01'] · FRED HUTCHINSON CANCER CENTER · NIH-10684841
This study is looking at how children and teens in Uganda get infected with a virus linked to Kaposi sarcoma, and it aims to understand the timing and reasons behind these infections to help improve prevention and treatment options.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FRED HUTCHINSON CANCER CENTER (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10684841 on ClinicalTrials.gov |
What this research studies
This research investigates the factors that contribute to the primary infection of Kaposi sarcoma-associated herpesvirus (KSHV) among children and adolescents in Uganda. By following households with mothers and young children, the study aims to identify when and how KSHV infections occur, as well as the biological and immunological factors involved. The research will utilize detailed cohort studies to track infections over time and analyze the dynamics of KSHV transmission. This comprehensive approach seeks to provide insights that could inform prevention and treatment strategies for KSHV-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents living in Uganda, particularly those who may be at risk for KSHV infection.
Not a fit: Patients outside of Uganda or those who are not children or adolescents may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating KSHV-related diseases in children and adolescents.
How similar studies have performed: Previous studies have successfully characterized herpesvirus infections in similar populations, suggesting that this approach may yield valuable insights.
Where this research is happening
SEATTLE, UNITED STATES
- FRED HUTCHINSON CANCER CENTER — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PHIPPS, WARREN — FRED HUTCHINSON CANCER CENTER
- Study coordinator: PHIPPS, WARREN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers