NIH-funded research R01 grant

Understanding how childhood obesity develops over time

Official title: Developmental trajectories of reinforcer pathology and childhood obesity

Funded at State University of New York at Buffalo · NIH-11043582 · Data updated 2026-11-12

This study looks at how kids' reasons for eating and being active change as they grow up, especially how their ability to wait for rewards affects their choices, to help understand what leads to obesity in young people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startMarch 15, 2025
Project endJanuary 31, 2030
Funding year2025
Award (this year)$695,295
NIH project number1R01DK139258-01A1
Project IDNIH-11043582 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include children and adolescents aged 0 to 20 years who are experiencing issues related to obesity or weight management.

Less likely to help

Patients who are not within the age range of 0 to 20 years or who do not have concerns related to obesity may not benefit from this research.

What this research studies

This research investigates how the motivations for eating and physical activity change as children grow, particularly focusing on the role of reward systems in decision-making. It examines how children's ability to delay gratification and make healthier choices evolves from childhood into adolescence and early adulthood. By studying the balance between the desire for food and the motivation to be active, the research aims to identify factors that contribute to obesity in youth. The study will utilize behavioral assessments to measure these motivations and their impact on weight gain.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for preventing and treating obesity in children and adolescents.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between reward systems and obesity, suggesting that this approach could yield valuable insights.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Epstein, Leonard H — State University of New York at Buffalo
  • Study coordinator: Epstein, Leonard H

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.