Understanding how childhood cancers respond to radiation
Official title: Administrative Core
Funded at Dana-Farber Cancer Inst · NIH-10931428 · Data updated 2026-11-12
This study is looking at how childhood cancers react to radiation treatment and why some resist it, with the goal of finding better ways to help kids and adults get the most effective care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $235,759 |
| NIH project number | 5U54CA274516-02 |
| Project ID | NIH-10931428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and young adults diagnosed with cancer, particularly those undergoing radiation therapy.
✕Less likely to help
Patients with cancers that do not involve radiation treatment or those outside the age range of 21 years and older may not benefit from this research.
What this research studies
This research investigates the molecular mechanisms behind how childhood cancers respond to and resist radiation treatment. By focusing on the unique genetic characteristics of pediatric cancers, the study aims to uncover insights that could improve treatment strategies for both children and adults. The project includes various components such as a Molecular Characterization Trial and advanced data science techniques to analyze the findings. Patients may benefit from improved radiation therapies tailored to their specific cancer types.
Why it matters
Potential benefit: If successful, this research could lead to more effective radiation treatments for childhood cancers, potentially improving survival rates and quality of life.
How similar studies have gone: Previous research has shown promise in understanding radiation resistance in cancers, suggesting that this approach could yield valuable insights.
Where this research is happening
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Dana-Farber Cancer Inst
Boston, United States Active
Researchers
- Principal investigator: Haas-Kogan, Daphne a. — Dana-Farber Cancer Inst
- Study coordinator: Haas-Kogan, Daphne a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.