Understanding how childhood cancers respond to radiation

Administrative Core

['FUNDING_OTHER'] · DANA-FARBER CANCER INST · NIH-10931428

This study is looking at how childhood cancers react to radiation treatment and why some resist it, with the goal of finding better ways to help kids and adults get the most effective care.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDANA-FARBER CANCER INST (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10931428 on ClinicalTrials.gov

What this research studies

This research investigates the molecular mechanisms behind how childhood cancers respond to and resist radiation treatment. By focusing on the unique genetic characteristics of pediatric cancers, the study aims to uncover insights that could improve treatment strategies for both children and adults. The project includes various components such as a Molecular Characterization Trial and advanced data science techniques to analyze the findings. Patients may benefit from improved radiation therapies tailored to their specific cancer types.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and young adults diagnosed with cancer, particularly those undergoing radiation therapy.

Not a fit: Patients with cancers that do not involve radiation treatment or those outside the age range of 21 years and older may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective radiation treatments for childhood cancers, potentially improving survival rates and quality of life.

How similar studies have performed: Previous research has shown promise in understanding radiation resistance in cancers, suggesting that this approach could yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.