Understanding how childhood adversity affects brain development and mental health.

Conceptual Models of Childhood Adversity: Multivariate and Neural Approaches

NIH-funded research University of Oregon · NIH-10932208

This study looks at how tough experiences in childhood affect brain development and mental health in teenage girls, and it also explores how positive experiences can help lessen those effects.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Oregon NIH-funded
Lab location1 site (Eugene, United States)
Project IDNIH-10932208 on NIH RePORTER

What this research studies

This research investigates the impact of childhood adverse experiences on brain development and mental health during adolescence. It aims to clarify how these experiences are processed in the brain and how positive experiences may buffer their effects. Using advanced computational techniques, the study will analyze data from a longitudinal sample of adolescent girls to evaluate different models of adversity and their relationship with mental health symptoms over time. By examining these factors, the research seeks to provide insights into the neurobiological mechanisms underlying childhood adversity.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescent girls aged 10-13 who have experienced varying levels of childhood adversity.

Not a fit: Patients who are outside the age range of 10-13 or who have not experienced childhood adversity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for mental health issues stemming from childhood adversity.

How similar studies have performed: Previous research has shown promising results in understanding the effects of childhood adversity on mental health, making this approach both relevant and potentially impactful.

Where this research is happening

Eugene, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.