Understanding how chikungunya virus and its mosquito carriers evolve together
Exploring the coevolutionary potential of chikungunya virus and its Aedes mosquito vectors
['FUNDING_R01'] · PENNSYLVANIA STATE UNIVERSITY, THE · NIH-11076240
This study is looking at how the mosquitoes that spread the chikungunya virus might change over time to resist the virus, which could help us find new ways to control these mosquitoes and lower the chances of getting chikungunya.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIVERSITY, THE (nih funded) |
| Locations | 1 site (UNIVERSITY PARK, UNITED STATES) |
| Trial ID | NIH-11076240 on ClinicalTrials.gov |
What this research studies
This research investigates the chikungunya virus (CHIKV) and its relationship with the Aedes mosquito species that transmit it. By examining how these mosquitoes might evolve resistance to the virus, the study aims to identify genetic factors that could help control the spread of CHIKV. The research employs experimental evolution techniques and advanced genome analysis to uncover potential genetic markers associated with virus resistance. This could lead to better strategies for managing mosquito populations and reducing the incidence of chikungunya infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in regions where chikungunya virus is endemic, particularly in Latin America and the Caribbean.
Not a fit: Patients who do not live in areas affected by chikungunya virus or those who have already been infected may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for controlling chikungunya virus transmission, potentially reducing the incidence of chronic arthritis associated with the infection.
How similar studies have performed: Other research has shown success in understanding the evolution of mosquito resistance to viruses, indicating that this approach could yield valuable insights.
Where this research is happening
UNIVERSITY PARK, UNITED STATES
- PENNSYLVANIA STATE UNIVERSITY, THE — UNIVERSITY PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCGRAW, ELIZABETH ANN — PENNSYLVANIA STATE UNIVERSITY, THE
- Study coordinator: MCGRAW, ELIZABETH ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.