Understanding how chemotherapy affects taste nerve recovery
Investigating alterations in gustatory neuron innervation and function over the course of chemotherapy treatment
This study looks at how chemotherapy affects the recovery of taste nerves in cancer patients, helping us understand why some people have ongoing taste changes after treatment with a common drug called cyclophosphamide.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11010352 on NIH RePORTER |
What this research studies
This research investigates how chemotherapy impacts the recovery of taste nerves in patients. It focuses on the changes in gustatory fiber innervation and taste signaling after treatment with cyclophosphamide, a common chemotherapy drug. By using advanced imaging techniques and nerve recordings, the study aims to track the timeline of nerve recovery and how it affects taste perception. The findings could provide insights into the prolonged taste disruptions experienced by cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults undergoing chemotherapy treatment, particularly those experiencing taste alterations.
Not a fit: Patients who are not undergoing chemotherapy or those without taste alterations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of taste alterations in chemotherapy patients, enhancing their quality of life during recovery.
How similar studies have performed: While some research has explored taste alterations in chemotherapy, this specific investigation into gustatory fiber recovery is novel and has not been extensively studied.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Wood, Ryan — University of Texas San Antonio
- Study coordinator: Wood, Ryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.