Understanding how chemical signals affect inflammation and immune responses
Deciphering the role of chemical signals in inflammation with open microfluidic functional assays - U3 Supplement
This study is looking at how tiny molecules and proteins help our cells talk to each other during inflammation and immune responses, especially when germs are around, and it aims to create easy ways for people to collect samples at home to keep track of their immune health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11018318 on NIH RePORTER |
What this research studies
This research investigates the role of small molecules and proteins in cellular communication, particularly in the context of inflammation and immune responses. By developing innovative microscale culture methods, the team aims to study how different cell types interact and how these interactions are influenced by the presence of microbes. The research includes creating specialized platforms for studying complex interactions between human cells, bacteria, and fungi, as well as methods for at-home sampling of biological fluids to monitor immune responses over time.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing inflammatory conditions or those affected by COVID-19.
Not a fit: Patients with non-inflammatory conditions or those not affected by COVID-19 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for inflammatory conditions, including those related to COVID-19.
How similar studies have performed: Other research has shown promise in understanding cellular signaling and inflammation, making this approach both relevant and potentially impactful.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Theberge, Ashleigh Brooks — University of Washington
- Study coordinator: Theberge, Ashleigh Brooks
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.