Understanding how chemical signals affect inflammation
Deciphering the role of chemical signals in inflammation with open microfluidic functional assays - Bouker Diversity Supplement
This study is looking at how tiny molecules and proteins help cells talk to each other, especially when it comes to inflammation, and it's designed for anyone interested in understanding how our immune system interacts with bacteria and fungi, including ways to track these changes from home.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11013272 on NIH RePORTER |
What this research studies
This research investigates the role of small molecules and proteins in cellular communication, particularly focusing on how these signals influence inflammation. By developing innovative microscale methods, the team aims to explore how different cell types interact and how the presence of microbes alters these interactions. The research includes creating specialized culture platforms to study complex relationships between human cells and bacteria or fungi, as well as methods for at-home sampling of biological fluids to monitor immune responses over time.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to inflammation or immune response.
Not a fit: Patients with non-inflammatory conditions or those not affected by immune system issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into inflammatory diseases and improve treatment strategies for patients.
How similar studies have performed: Previous research has shown promise in understanding cell signaling and inflammation, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Theberge, Ashleigh Brooks — University of Washington
- Study coordinator: Theberge, Ashleigh Brooks
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.