Understanding how chemical injuries affect human skin and finding ways to treat them
Explant human skin perfusion model to study mechanisms of chemical injury and mitigation
This study is looking at how harmful chemicals can hurt the skin and aims to find better ways to treat those injuries, so people who might be exposed to these chemicals can have improved care and recovery options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10997376 on NIH RePORTER |
What this research studies
This research investigates the effects of chemical agents that can cause severe skin injuries, particularly in the context of potential mass exposure scenarios. Using a specialized human skin perfusion model, the team aims to explore how human skin responds to these harmful substances and to identify effective treatments. The study will involve rigorous testing of skin responses and the mechanisms behind these injuries, with the goal of developing better countermeasures for chemical injuries. Patients may benefit from advancements in treatment options for chemical-induced skin damage.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who may be at risk of exposure to chemical agents, such as first responders or military personnel.
Not a fit: Patients who have not been exposed to chemical agents or who have pre-existing skin conditions unrelated to chemical injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective therapies for treating chemical-induced skin injuries, improving patient outcomes in emergency situations.
How similar studies have performed: While there have been studies on chemical injuries, this specific approach using a human skin perfusion model is relatively novel and aims to fill a critical gap in understanding and treatment.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Ejaz, Asim — University of Pittsburgh at Pittsburgh
- Study coordinator: Ejaz, Asim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.