Understanding how chemical exposure harms the eyes

The mechanism of vesicant-induced ocular injury

['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-11250199

This study is looking into how certain harmful chemicals can hurt your eyes, both right away and even years later, to find better ways to protect your vision and treat any damage.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (WINSTON-SALEM, UNITED STATES)
Trial IDNIH-11250199 on ClinicalTrials.gov

What this research studies

This research investigates the effects of vesicant exposure on the eyes, which are particularly vulnerable to such chemicals. The study aims to uncover the molecular mechanisms that lead to both immediate and long-term ocular damage, including conditions that may develop years after exposure. By analyzing how these chemicals affect various eye tissues, the researchers hope to identify potential treatments to prevent or mitigate vision loss. This work is crucial as current medical options to address vesicant-induced eye injuries are lacking.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced exposure to vesicants or similar chemical agents.

Not a fit: Patients with ocular injuries not related to chemical exposure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective treatments for preventing vision loss caused by chemical exposure.

How similar studies have performed: While the specific focus on vesicant-induced ocular injury is novel, similar research has shown promise in understanding chemical exposure effects on other organs.

Where this research is happening

WINSTON-SALEM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.