NIH-funded research R01 grant

Understanding how chemical exposure harms the eyes

Official title: The mechanism of vesicant-induced ocular injury

Funded at Wake Forest University Health Sciences · NIH-11250199 · Data updated 2026-11-12

This study is looking into how certain harmful chemicals can hurt your eyes, both right away and even years later, to find better ways to protect your vision and treat any damage.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences
NIH-funded
Lab location1 site (Winston-Salem, United States)
Project startDecember 21, 2024
Project endFebruary 28, 2026
Funding year2024
Award (this year)$426,367
NIH project number7R01EY034110-04
Project IDNIH-11250199 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals who have experienced exposure to vesicants or similar chemical agents.

Less likely to help

Patients with ocular injuries not related to chemical exposure may not benefit from this research.

What this research studies

This research investigates the effects of vesicant exposure on the eyes, which are particularly vulnerable to such chemicals. The study aims to uncover the molecular mechanisms that lead to both immediate and long-term ocular damage, including conditions that may develop years after exposure. By analyzing how these chemicals affect various eye tissues, the researchers hope to identify potential treatments to prevent or mitigate vision loss. This work is crucial as current medical options to address vesicant-induced eye injuries are lacking.

Why it matters

Potential benefit: If successful, this research could lead to effective treatments for preventing vision loss caused by chemical exposure.

How similar studies have gone: While the specific focus on vesicant-induced ocular injury is novel, similar research has shown promise in understanding chemical exposure effects on other organs.

Where this research is happening

  • Wake Forest University Health Sciences
    Winston-Salem, United States
    Active

Researchers

  • Principal investigator: Gorbatyuk, Marina — Wake Forest University Health Sciences
  • Study coordinator: Gorbatyuk, Marina

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.