Understanding how chaotic blood flow shapes health and disease
Official title: The physiological and biomedical implications of chaos in fluid flow: fundamental theoretical, computational, andexperimental investigations
Funded at University of Colorado · NIH-11431002 · Data updated 2026-11-12
A research program to reveal how chaotic fluid movement affects blood clotting, blood vessels, drug delivery, and tiny lab devices, with the goal of improving health care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project start | September 1, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $410,012 |
| NIH project number | 1R35GM166667-01 |
| Project ID | NIH-11431002 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients with clotting disorders, vascular diseases, or conditions where microfluidic devices are used clinically or in research.
✕Less likely to help
Patients not involved in clotting or vascular health or those not connected to flows in biomedical devices may not directly benefit.
What this research studies
This project uses computer simulations and lab experiments to create easy-to-use tools that describe chaotic flows in the body. It will study how chaotic motion influences mixing of substances and how cells and proteins respond to these forces. The team will build fast, high-resolution analyses and apply them to physiological and biomedical flow scenarios. The work aims to turn complex chaos into clear metrics that clinicians and researchers can use to understand and treat conditions related to blood and vascular health.
Why it matters
Potential benefit: If successful, this work could lead to better predictions of where clots form and how drugs spread in the body, improving patient safety and treatment effectiveness.
How similar studies have gone: Previous studies have shown that flow patterns influence biological processes, but this project aims to provide new, interpretable descriptors for chaotic flows.
Where this research is happening
-
University of Colorado
Boulder, United States Active
Researchers
- Principal investigator: Mukherjee, Debanjan — University of Colorado
- Study coordinator: Mukherjee, Debanjan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.