Understanding how changes in the brain affect social behaviors related to smell.
Neuroplasticity in chemosensory-mediated social behaviors
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10988271
This study looks at how the brain's ability to change affects how ants use their sense of smell to communicate and behave socially, and it hopes to help us understand similar processes in humans, especially for people with conditions like Alzheimer's and autism.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10988271 on ClinicalTrials.gov |
What this research studies
This research investigates how neuroplasticity, or the brain's ability to adapt, influences social behaviors that are mediated by the sense of smell. By studying ants, which exhibit complex social interactions and significant neuroplasticity, the researchers aim to uncover the mechanisms behind olfactory-related social behaviors. The study utilizes genetic tools to manipulate and observe changes in the olfactory system and its impact on social communication and behavior. This approach may provide insights into how similar processes occur in humans, particularly in relation to conditions like Alzheimer's disease and autism.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing social isolation or have conditions such as Alzheimer's disease or autism.
Not a fit: Patients who do not have any olfactory-related issues or social behavior challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving social interactions and quality of life for individuals affected by neurodegenerative diseases and social disorders.
How similar studies have performed: Previous research has shown promising results in understanding neuroplasticity and social behaviors in animal models, suggesting potential for similar insights in humans.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YAN, HUA — UNIVERSITY OF FLORIDA
- Study coordinator: YAN, HUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome