Understanding how changes in eye structure relate to vision loss in glaucoma
Relating Structure to Function in Optic Neuropathies
This study is looking at how the optic nerve's structure affects eye function in people with glaucoma, with the goal of finding better ways to detect the condition early and understand how it progresses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10547776 on NIH RePORTER |
What this research studies
This research investigates the relationship between the structure of the optic nerve and the function of the eye in patients with glaucoma, a condition that can lead to irreversible vision loss. The study will use advanced imaging techniques and experimental models to explore how changes in the optic nerve head and surrounding tissues contribute to the loss of retinal ganglion cells, which are crucial for vision. By examining these relationships, the research aims to improve the understanding of glaucoma progression and develop better diagnostic tools for early detection.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with glaucoma or those at high risk due to factors such as family history, age, or elevated intraocular pressure.
Not a fit: Patients with other types of optic neuropathies unrelated to glaucoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for diagnosing and monitoring glaucoma, potentially preserving vision for patients at risk.
How similar studies have performed: Previous research has shown promising results in understanding the structural changes in glaucoma, but this specific approach using advanced imaging techniques is relatively novel.
Where this research is happening
Houston, United States
- University of Houston — Houston, United States (Active)
Researchers
- Principal investigator: Patel, Nimesh Bhikhu — University of Houston
- Study coordinator: Patel, Nimesh Bhikhu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.