Understanding how certain retinal cells detect motion direction

Mechanisms of direction selectivity in starburst amacrine cells

NIH-funded research University of Colorado Denver · NIH-10751007

This study looks at how special cells in the eye help us see and understand which way things are moving, and it hopes to find new ways to improve vision for people with visual disorders.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-10751007 on NIH RePORTER

What this research studies

This research investigates how starburst amacrine cells in the retina process visual information to detect motion direction. By examining the intricate mechanisms that allow these cells to transform non-directional signals into directional outputs, the study aims to uncover the fundamental principles of visual processing in the brain. The approach includes detailed electrophysiological techniques and numerical simulations to analyze the cellular functions and interactions involved in this process. Patients may benefit from insights gained into visual perception and potential treatments for visual disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit include individuals with visual perception issues or those interested in the underlying mechanisms of vision.

Not a fit: Patients with conditions unrelated to visual processing or those not experiencing any visual perception issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for visual processing disorders.

How similar studies have performed: Previous research has shown success in understanding similar mechanisms in visual processing, indicating a promising avenue for further exploration.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.