Understanding how certain proteins regulate cell functions
Protein Phosphatase 1 Holoenzyme Formation
This study is looking at how certain proteins help control important processes in our cells, which can affect things like growth and development, and it aims to understand how problems with these proteins might lead to diseases like cancer, so that we can find new ways to treat patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-10913337 on NIH RePORTER |
What this research studies
This research investigates the role of specific proteins known as phosphatases in regulating the phosphorylation state of cells, which is crucial for various biological processes such as cell growth and differentiation. By examining the mechanisms of two essential regulators, SDS22 and Inhibitor-3, the research aims to uncover their biological functions and how their dysregulation can lead to diseases, including cancer. The approach involves biochemical techniques to analyze protein interactions and functions within cells, providing insights into cellular signaling pathways. Patients may benefit from a deeper understanding of these processes, potentially leading to new therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with cancers or other diseases related to cell signaling dysregulation.
Not a fit: Patients with conditions unrelated to cellular signaling or those who do not have cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases caused by dysregulated cell signaling, including various cancers.
How similar studies have performed: Other research has shown success in understanding protein regulation in cellular processes, indicating that this approach has potential for meaningful discoveries.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Peti, Wolfgang — University of Connecticut Sch of Med/dnt
- Study coordinator: Peti, Wolfgang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.